Tumor texture analysis in PET: Relationship between the level of uptake of radio-label at the time of treatment and the level of uptake of radio-label before and after treatment

In this paper we present an analysis of relationship between the level of uptake of radio-label at the time of treatment and the level of uptake of radio-label before and after treatment. The analysis is based on correlation analysis of the tumor features. The patients had 3 examinations: before, during, and after the therapy within 1 month. The fusion of the examinations was performed and the tumors were designated. Then, 108 features were calculated. 3 features determine the tumor: maximum, minimum and average value of Standardized Uptake Value (SUV). 105 features are the texture indices indices based on histogram, histogram of sums, histogram of differences and co-occurrence matrix. The relationship between the features and the uptake levels was analyzed using the Pearson correlation. 29 features proved to be relevant for the correlation.