Singularity of optimal antiangiogenic strategies - Exception or rule

A. Swierniak; J. Smieja

Singularity of optimal antiangiogenic strategies - Exception or rule

Katedra Inżynierii i Biologii Systemów (RAU/RAU1)

Wyniki badań: Rozdział w książce/raport/materiał konferencyjny › Wkład w konferencję › recenzja

1 Cytowanie z bazy Scopus

Abstrakt

Six models of antiangiogenic therapy are compared and analyzed taking into account properties of strategies obtained in the process of optimization of its protocols. All of them consist of a model of tumor growth bounded by the capacity of a vascular network developed by the tumor in the process of angiogenesis and different models of dynamics of this network and they are modifications of the model proposed by Hahnfeldt et al. We analyse optimal control problems resulted from their use and we demonstrate that for five of them the optimal control has no singular arcs.

Język oryginału	angielski
Tytuł publikacji goszczącej	Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010
Strony	297-302
Liczba stron	6
Status publikacji	Opublikowano - 2010
Wydarzenie	7th IASTED International Conference on Biomedical Engineering, BioMED 2010 - Innsbruck, Austria Czas trwania: 17 lut 2010 → 19 lut 2010

Seria publikacji

Nazwa	Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010
Tom	1

Konferencja

Konferencja	7th IASTED International Conference on Biomedical Engineering, BioMED 2010
Kraj/Terytorium	Austria
Miejscowość	Innsbruck
Okres	17/02/10 → 19/02/10

Cele SDG ONZ

Ten wynik przyczynia się do realizacji następujących celów zrównoważonego rozwoju

Cel 3 Dobre zdrowie i dobre samopoczucie

Obszary tematyczne ASJC Scopus

Inżynieria biomedyczna
Medycyna (różne)

Inne pliki i linki

Link do publikacji w Scopus

Cytowanie

@inproceedings{8e971af8b6f849eebb007154b0268da0,

title = "Singularity of optimal antiangiogenic strategies - Exception or rule",

abstract = "Six models of antiangiogenic therapy are compared and analyzed taking into account properties of strategies obtained in the process of optimization of its protocols. All of them consist of a model of tumor growth bounded by the capacity of a vascular network developed by the tumor in the process of angiogenesis and different models of dynamics of this network and they are modifications of the model proposed by Hahnfeldt et al. We analyse optimal control problems resulted from their use and we demonstrate that for five of them the optimal control has no singular arcs.",

keywords = "Cancer, Drug delivery and pharmacokinetics, Dynamic systems, Optimal control",

author = "A. Swierniak and J. Smieja",

year = "2010",

language = "English",

isbn = "9780889868250",

series = "Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010",

pages = "297--302",

booktitle = "Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010",

note = "7th IASTED International Conference on Biomedical Engineering, BioMED 2010 ; Conference date: 17-02-2010 Through 19-02-2010",

}

Swierniak, A & Smieja, J 2010, Singularity of optimal antiangiogenic strategies - Exception or rule. w Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010. Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010, tom 1, str. 297-302, 7th IASTED International Conference on Biomedical Engineering, BioMED 2010, Innsbruck, Austria, 17/02/10.

Singularity of optimal antiangiogenic strategies - Exception or rule. / Swierniak, A.; Smieja, J.
Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010. 2010. str. 297-302 (Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010; Tom 1).

Wyniki badań: Rozdział w książce/raport/materiał konferencyjny › Wkład w konferencję › recenzja

TY - GEN

T1 - Singularity of optimal antiangiogenic strategies - Exception or rule

AU - Swierniak, A.

AU - Smieja, J.

PY - 2010

Y1 - 2010

N2 - Six models of antiangiogenic therapy are compared and analyzed taking into account properties of strategies obtained in the process of optimization of its protocols. All of them consist of a model of tumor growth bounded by the capacity of a vascular network developed by the tumor in the process of angiogenesis and different models of dynamics of this network and they are modifications of the model proposed by Hahnfeldt et al. We analyse optimal control problems resulted from their use and we demonstrate that for five of them the optimal control has no singular arcs.

AB - Six models of antiangiogenic therapy are compared and analyzed taking into account properties of strategies obtained in the process of optimization of its protocols. All of them consist of a model of tumor growth bounded by the capacity of a vascular network developed by the tumor in the process of angiogenesis and different models of dynamics of this network and they are modifications of the model proposed by Hahnfeldt et al. We analyse optimal control problems resulted from their use and we demonstrate that for five of them the optimal control has no singular arcs.

KW - Cancer

KW - Drug delivery and pharmacokinetics

KW - Dynamic systems

KW - Optimal control

UR - https://www.scopus.com/pages/publications/79953830436

M3 - Conference contribution

AN - SCOPUS:79953830436

SN - 9780889868250

T3 - Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010

SP - 297

EP - 302

BT - Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010

T2 - 7th IASTED International Conference on Biomedical Engineering, BioMED 2010

Y2 - 17 February 2010 through 19 February 2010

ER -

Singularity of optimal antiangiogenic strategies - Exception or rule

Abstrakt

Seria publikacji

Konferencja

Cele SDG ONZ

Obszary tematyczne ASJC Scopus

Inne pliki i linki

Fingerprint

Cytowanie