Optimization of antiangiogenic therapy as optimal control problem

Andrzej Swierniak; Grzegorz Gala; Alberto Gandolfi; Alberto D'Onofrio

Optimization of antiangiogenic therapy as optimal control problem

Andrzej Swierniak
, Grzegorz Gala
, Alberto Gandolfi
, Alberto D'Onofrio

Katedra Inżynierii i Biologii Systemów (RAU/RAU1)

Maria Sklodowska-Curie Institute of Oncology
Istituto di Analisi dei Sistemi ed Informatica
IRCCS Istituto Europeo di Oncologia - Milano

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27 Cytowania z bazy Scopus

Abstrakt

A model of antiangiogenic cancer chemotherapy is proposed and analyzed. The model is a modified Hahnfeldt model and the analysis has two goals: first of all we check stability of the equilibrium point of the model to find conditions leading to tumour eradication then we propose an optimization problem and give necessary conditions of its solution.

Język oryginału	angielski
Tytuł publikacji goszczącej	Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006
Strony	56-59
Liczba stron	4
Status publikacji	Opublikowano - 2006
Wydarzenie	4th IASTED International Conference on Biomechanics, BioMech 2006 - Palma de Mallorca, Hiszpania Czas trwania: 28 sie 2006 → 29 sie 2006

Seria publikacji

Nazwa	Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006

Konferencja

Konferencja	4th IASTED International Conference on Biomechanics, BioMech 2006
Kraj/Terytorium	Hiszpania
Miejscowość	Palma de Mallorca
Okres	28/08/06 → 29/08/06

Cele SDG ONZ

Ten wynik przyczynia się do realizacji następujących celów zrównoważonego rozwoju

Cel 3 Dobre zdrowie i dobre samopoczucie

Obszary tematyczne ASJC Scopus

Biofizyka
Inżynieria mechaniczna

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@inproceedings{7b47c010bd9e48f0a88a8455fc104d41,

title = "Optimization of antiangiogenic therapy as optimal control problem",

abstract = "A model of antiangiogenic cancer chemotherapy is proposed and analyzed. The model is a modified Hahnfeldt model and the analysis has two goals: first of all we check stability of the equilibrium point of the model to find conditions leading to tumour eradication then we propose an optimization problem and give necessary conditions of its solution.",

keywords = "Angiogenesis, Anticancer therapy, Drug delivery, Modeling, Simulation, Systems and control",

author = "Andrzej Swierniak and Grzegorz Gala and Alberto Gandolfi and Alberto D'Onofrio",

year = "2006",

language = "English",

isbn = "9780889866041",

series = "Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006",

pages = "56--59",

booktitle = "Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006",

note = "4th IASTED International Conference on Biomechanics, BioMech 2006 ; Conference date: 28-08-2006 Through 29-08-2006",

}

Swierniak, A, Gala, G, Gandolfi, A & D'Onofrio, A 2006, Optimization of antiangiogenic therapy as optimal control problem. w Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006. Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006, str. 56-59, 4th IASTED International Conference on Biomechanics, BioMech 2006, Palma de Mallorca, Hiszpania, 28/08/06.

Optimization of antiangiogenic therapy as optimal control problem. / Swierniak, Andrzej; Gala, Grzegorz; Gandolfi, Alberto i in.
Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006. 2006. str. 56-59 (Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006).

Wyniki badań: Rozdział w książce/raport/materiał konferencyjny › Wkład w konferencję › recenzja

TY - GEN

T1 - Optimization of antiangiogenic therapy as optimal control problem

AU - Swierniak, Andrzej

AU - Gala, Grzegorz

AU - Gandolfi, Alberto

AU - D'Onofrio, Alberto

PY - 2006

Y1 - 2006

N2 - A model of antiangiogenic cancer chemotherapy is proposed and analyzed. The model is a modified Hahnfeldt model and the analysis has two goals: first of all we check stability of the equilibrium point of the model to find conditions leading to tumour eradication then we propose an optimization problem and give necessary conditions of its solution.

AB - A model of antiangiogenic cancer chemotherapy is proposed and analyzed. The model is a modified Hahnfeldt model and the analysis has two goals: first of all we check stability of the equilibrium point of the model to find conditions leading to tumour eradication then we propose an optimization problem and give necessary conditions of its solution.

KW - Angiogenesis

KW - Anticancer therapy

KW - Drug delivery

KW - Modeling

KW - Simulation

KW - Systems and control

UR - https://www.scopus.com/pages/publications/38349139013

M3 - Conference contribution

AN - SCOPUS:38349139013

SN - 9780889866041

T3 - Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006

SP - 56

EP - 59

BT - Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006

T2 - 4th IASTED International Conference on Biomechanics, BioMech 2006

Y2 - 28 August 2006 through 29 August 2006

ER -

Optimization of antiangiogenic therapy as optimal control problem

Abstrakt

Seria publikacji

Konferencja

Cele SDG ONZ

Obszary tematyczne ASJC Scopus

Inne pliki i linki

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