TY - GEN
T1 - From micro-scale reactors to macro-scale process control
T2 - 2013 18th International Conference on Methods and Models in Automation and Robotics, MMAR 2013
AU - Choinski, Dariusz
AU - Niedzwiedz, Malgorzata
PY - 2013
Y1 - 2013
N2 - Designing an algorithm which allows automated seeking of the best operating point of a biological system is a quite complex task. That task is the subject of research for i.a. metabolic engineering which deals with control related issues, in particular with modeling of a biological phenomena kinetics as well as monitoring the unstable states of biomass growth. In the paper a theoretical analysis is described to present the utility of a microreactor application for designing, optimizing and controlling a biotechnological process. Moreover an attention to the hierarchical structure of phenomena and cyclical changes in metabolic state was paid. Models that are presented enable making connection between a bioprocess studied in micro-scale and a process operated in macro-scale. The paper indicates chip calorimetric measurements as a potential solution for the task in hand.
AB - Designing an algorithm which allows automated seeking of the best operating point of a biological system is a quite complex task. That task is the subject of research for i.a. metabolic engineering which deals with control related issues, in particular with modeling of a biological phenomena kinetics as well as monitoring the unstable states of biomass growth. In the paper a theoretical analysis is described to present the utility of a microreactor application for designing, optimizing and controlling a biotechnological process. Moreover an attention to the hierarchical structure of phenomena and cyclical changes in metabolic state was paid. Models that are presented enable making connection between a bioprocess studied in micro-scale and a process operated in macro-scale. The paper indicates chip calorimetric measurements as a potential solution for the task in hand.
UR - https://www.scopus.com/pages/publications/84893449913
U2 - 10.1109/mmar.2013.6669985
DO - 10.1109/mmar.2013.6669985
M3 - Conference contribution
AN - SCOPUS:84893449913
SN - 9781467355063
T3 - 2013 18th International Conference on Methods and Models in Automation and Robotics, MMAR 2013
SP - 639
EP - 644
BT - 2013 18th International Conference on Methods and Models in Automation and Robotics, MMAR 2013
PB - IEEE Computer Society
Y2 - 26 August 2013 through 29 August 2013
ER -