Comparison of controllability conditions for models of antiangiogenic and combined anticancer therapy

Andrzej ͆wierniak; Jerzy Klamka

Comparison of controllability conditions for models of antiangiogenic and combined anticancer therapy

Andrzej ͆wierniak
, Jerzy Klamka

Katedra Pomiarów i Systemów Sterowania (RAU/RAU2)

Silesian University of Technology

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Abstrakt

We compare sufficient conditions for local controllability for a class of models of treatment response to antiangiogenic and combined anticancer therapies. The combined therapy is understood as combination of direct anticancer strategy e.g. chemotherapy and indirect modality (in this case antiangiogenic therapy). We discuss different control objectives related to multimodal therapies in the light of present knowledge of self-organization of tumor cell populations treated by anticancer drugs. Controllability of the models in the form of semilinear second order dynamic systems enables to expect that the objectives could be reached.

Język oryginału	angielski
Tytuł publikacji goszczącej	19th IFAC World Congress IFAC 2014, Proceedings
Redaktorzy	Xiaohua Xia, Edward Boje
Wydawca	IFAC Secretariat
Strony	11530-11535
Liczba stron	6
ISBN (elektroniczny)	9783902823625
Status publikacji	Opublikowano - 2014
Wydarzenie	19th IFAC World Congress on International Federation of Automatic Control, IFAC 2014 - Cape Town, Republika Południowej Afryki Czas trwania: 24 sie 2014 → 29 sie 2014

Seria publikacji

Nazwa	IFAC Proceedings Volumes (IFAC-PapersOnline)
Tom	19
ISSN (drukowany)	1474-6670

Konferencja

Konferencja	19th IFAC World Congress on International Federation of Automatic Control, IFAC 2014
Kraj/Terytorium	Republika Południowej Afryki
Miejscowość	Cape Town
Okres	24/08/14 → 29/08/14

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Cel 3 Dobre zdrowie i dobre samopoczucie

Obszary tematyczne ASJC Scopus

Inżynieria sterowania i systemów

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Cytowanie

@inproceedings{25636beda55a4d37906b04dde0b4f8af,

title = "Comparison of controllability conditions for models of antiangiogenic and combined anticancer therapy",

abstract = "We compare sufficient conditions for local controllability for a class of models of treatment response to antiangiogenic and combined anticancer therapies. The combined therapy is understood as combination of direct anticancer strategy e.g. chemotherapy and indirect modality (in this case antiangiogenic therapy). We discuss different control objectives related to multimodal therapies in the light of present knowledge of self-organization of tumor cell populations treated by anticancer drugs. Controllability of the models in the form of semilinear second order dynamic systems enables to expect that the objectives could be reached.",

keywords = "Cancer modeling, Constrained controllability, Multimodal therapy, Semilinear systems",

author = "Andrzej ͆wierniak and Jerzy Klamka",

note = "Publisher Copyright: {\textcopyright} IFAC.; 19th IFAC World Congress on International Federation of Automatic Control, IFAC 2014 ; Conference date: 24-08-2014 Through 29-08-2014",

year = "2014",

language = "English",

series = "IFAC Proceedings Volumes (IFAC-PapersOnline)",

publisher = "IFAC Secretariat",

pages = "11530--11535",

editor = "Xiaohua Xia and Edward Boje",

booktitle = "19th IFAC World Congress IFAC 2014, Proceedings",

}

͆wierniak, A & Klamka, J 2014, Comparison of controllability conditions for models of antiangiogenic and combined anticancer therapy. w X Xia & E Boje (red), 19th IFAC World Congress IFAC 2014, Proceedings. IFAC Proceedings Volumes (IFAC-PapersOnline), tom 19, IFAC Secretariat, str. 11530-11535, 19th IFAC World Congress on International Federation of Automatic Control, IFAC 2014, Cape Town, Republika Południowej Afryki, 24/08/14.

Comparison of controllability conditions for models of antiangiogenic and combined anticancer therapy. / ͆wierniak, Andrzej; Klamka, Jerzy.
19th IFAC World Congress IFAC 2014, Proceedings. red. / Xiaohua Xia; Edward Boje. IFAC Secretariat, 2014. str. 11530-11535 (IFAC Proceedings Volumes (IFAC-PapersOnline); Tom 19).

Wyniki badań: Rozdział w książce/raport/materiał konferencyjny › Wkład w konferencję › recenzja

TY - GEN

T1 - Comparison of controllability conditions for models of antiangiogenic and combined anticancer therapy

AU - ͆wierniak, Andrzej

AU - Klamka, Jerzy

N1 - Publisher Copyright: © IFAC.

PY - 2014

Y1 - 2014

N2 - We compare sufficient conditions for local controllability for a class of models of treatment response to antiangiogenic and combined anticancer therapies. The combined therapy is understood as combination of direct anticancer strategy e.g. chemotherapy and indirect modality (in this case antiangiogenic therapy). We discuss different control objectives related to multimodal therapies in the light of present knowledge of self-organization of tumor cell populations treated by anticancer drugs. Controllability of the models in the form of semilinear second order dynamic systems enables to expect that the objectives could be reached.

AB - We compare sufficient conditions for local controllability for a class of models of treatment response to antiangiogenic and combined anticancer therapies. The combined therapy is understood as combination of direct anticancer strategy e.g. chemotherapy and indirect modality (in this case antiangiogenic therapy). We discuss different control objectives related to multimodal therapies in the light of present knowledge of self-organization of tumor cell populations treated by anticancer drugs. Controllability of the models in the form of semilinear second order dynamic systems enables to expect that the objectives could be reached.

KW - Cancer modeling

KW - Constrained controllability

KW - Multimodal therapy

KW - Semilinear systems

UR - https://www.scopus.com/pages/publications/84929791717

M3 - Conference contribution

AN - SCOPUS:84929791717

T3 - IFAC Proceedings Volumes (IFAC-PapersOnline)

SP - 11530

EP - 11535

BT - 19th IFAC World Congress IFAC 2014, Proceedings

A2 - Xia, Xiaohua

A2 - Boje, Edward

PB - IFAC Secretariat

T2 - 19th IFAC World Congress on International Federation of Automatic Control, IFAC 2014

Y2 - 24 August 2014 through 29 August 2014

ER -

Comparison of controllability conditions for models of antiangiogenic and combined anticancer therapy

Abstrakt

Seria publikacji

Konferencja

Cele SDG ONZ

Obszary tematyczne ASJC Scopus

Inne pliki i linki

Fingerprint

Cytowanie