Adducts of uridine and glycals as potential substrates for glycosyltransferases

Ilona Wandzik; Tadeusz Bieg

doi:10.1016/j.bioorg.2007.07.001

Adducts of uridine and glycals as potential substrates for glycosyltransferases

Katedra Chemii Organicznej, Bioorganicznej i Biotechnologii (RCH/RCH2)

Wyniki badań: Wkład do czasopisma › Artykuł › recenzja

10 Cytowania z bazy Scopus

Abstrakt

We report on the synthesis of 2-deoxyglycosyl derivatives of uridine as potential donor substrates for glycosyltransferases. The totally stereoselective synthesis is accomplished by two sequential addition reactions of uridine derivatives to glycals promoted by triphenylphosphine-hydrogen bromide.

Język oryginału	angielski
Strony (od–do)	401-416
Liczba stron	16
Czasopismo	Bioorganic Chemistry
Tom	35
Numer wydania	5
Identyfikatory DOI	https://doi.org/10.1016/j.bioorg.2007.07.001
Status publikacji	Opublikowano - paź 2007

Obszary tematyczne ASJC Scopus

Biochemia
Biologia molekularna
Odkrywanie leków
Chemia organiczna

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10.1016/j.bioorg.2007.07.001

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Cytowanie

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title = "Adducts of uridine and glycals as potential substrates for glycosyltransferases",

abstract = "We report on the synthesis of 2-deoxyglycosyl derivatives of uridine as potential donor substrates for glycosyltransferases. The totally stereoselective synthesis is accomplished by two sequential addition reactions of uridine derivatives to glycals promoted by triphenylphosphine-hydrogen bromide.",

keywords = "GTs substrate analogues, Glycals, Stereoselective synthesis",

author = "Ilona Wandzik and Tadeusz Bieg",

year = "2007",

month = oct,

doi = "10.1016/j.bioorg.2007.07.001",

language = "English",

volume = "35",

pages = "401--416",

journal = "Bioorganic Chemistry",

issn = "0045-2068",

publisher = "Academic Press Inc.",

number = "5",

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TY - JOUR

T1 - Adducts of uridine and glycals as potential substrates for glycosyltransferases

AU - Wandzik, Ilona

AU - Bieg, Tadeusz

PY - 2007/10

Y1 - 2007/10

N2 - We report on the synthesis of 2-deoxyglycosyl derivatives of uridine as potential donor substrates for glycosyltransferases. The totally stereoselective synthesis is accomplished by two sequential addition reactions of uridine derivatives to glycals promoted by triphenylphosphine-hydrogen bromide.

AB - We report on the synthesis of 2-deoxyglycosyl derivatives of uridine as potential donor substrates for glycosyltransferases. The totally stereoselective synthesis is accomplished by two sequential addition reactions of uridine derivatives to glycals promoted by triphenylphosphine-hydrogen bromide.

KW - GTs substrate analogues

KW - Glycals

KW - Stereoselective synthesis

UR - https://www.scopus.com/pages/publications/34548120609

U2 - 10.1016/j.bioorg.2007.07.001

DO - 10.1016/j.bioorg.2007.07.001

M3 - Article

C2 - 17707879

AN - SCOPUS:34548120609

SN - 0045-2068

VL - 35

SP - 401

EP - 416

JO - Bioorganic Chemistry

JF - Bioorganic Chemistry

IS - 5

ER -

Adducts of uridine and glycals as potential substrates for glycosyltransferases

Abstrakt

Obszary tematyczne ASJC Scopus

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