Three levels of objects of control in anticancer therapy

Andrzej Świerniak

doi:10.1109/MMAR.2012.6347852

Three levels of objects of control in anticancer therapy

Andrzej Świerniak

Department of Systems Biology and Engineering (RAU/RAU1)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Three types of models used to represent the object of control in anticancer therapies are presented. The first approach is based on the idea that chemotherapy may be treated as control action with cell-cycle as an object of control. In the second approach population dynamics models are used to describe anticancer treatment in antiangiogenic and combined therapies. The last level on which we consider control problems resulting from anticancer actions is related to gene signaling pathway models. In this case we propose the use of interfering RNA to aid radiotherapy by silencing the negative feedback in p53 protein regulatory module.

Original language	English
Title of host publication	2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012
Pages	421-426
Number of pages	6
DOIs	https://doi.org/10.1109/MMAR.2012.6347852
Publication status	Published - 2012
Event	2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012 - Miedzyzdroje, Poland Duration: 27 Aug 2012 → 30 Aug 2012

Publication series

Name	2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012

Conference

Conference	2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012
Country/Territory	Poland
City	Miedzyzdroje
Period	27/08/12 → 30/08/12

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Artificial Intelligence
Human-Computer Interaction

Access to Document

10.1109/MMAR.2012.6347852

Cite this

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title = "Three levels of objects of control in anticancer therapy",

abstract = "Three types of models used to represent the object of control in anticancer therapies are presented. The first approach is based on the idea that chemotherapy may be treated as control action with cell-cycle as an object of control. In the second approach population dynamics models are used to describe anticancer treatment in antiangiogenic and combined therapies. The last level on which we consider control problems resulting from anticancer actions is related to gene signaling pathway models. In this case we propose the use of interfering RNA to aid radiotherapy by silencing the negative feedback in p53 protein regulatory module.",

author = "Andrzej {\'S}wierniak",

year = "2012",

doi = "10.1109/MMAR.2012.6347852",

language = "English",

isbn = "9781467321211",

series = "2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012",

pages = "421--426",

booktitle = "2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012",

note = "2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012 ; Conference date: 27-08-2012 Through 30-08-2012",

}

Świerniak, A 2012, Three levels of objects of control in anticancer therapy. in 2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012., 6347852, 2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012, pp. 421-426, 2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012, Miedzyzdroje, Poland, 27/08/12. https://doi.org/10.1109/MMAR.2012.6347852

Three levels of objects of control in anticancer therapy. / Świerniak, Andrzej.
2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012. 2012. p. 421-426 6347852 (2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AB - Three types of models used to represent the object of control in anticancer therapies are presented. The first approach is based on the idea that chemotherapy may be treated as control action with cell-cycle as an object of control. In the second approach population dynamics models are used to describe anticancer treatment in antiangiogenic and combined therapies. The last level on which we consider control problems resulting from anticancer actions is related to gene signaling pathway models. In this case we propose the use of interfering RNA to aid radiotherapy by silencing the negative feedback in p53 protein regulatory module.

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DO - 10.1109/MMAR.2012.6347852

M3 - Conference contribution

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BT - 2012 17th International Conference on Methods and Models in Automation and Robotics, MMAR 2012

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Three levels of objects of control in anticancer therapy

Abstract

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Conference

UN SDGs

ASJC Scopus subject areas

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