The influence of silver nanoparticles introduced into RTV-silicone matrix on the activity against Streptococcus mutans

Purpose: The silicone based room temperature vulcanized (RTV) polymers are commonly used materials for medicine, especially for dentures and maxillofacial prostheses. Unfortunately, the colonization of those materials by pathogenic microorganisms is well-known problem related with their applications. The aim of presented study was to examine antibacterial properties of RTV silicone for dentistry modified with silver nanoparticles. Design/methodology/approach: The silver nanoparticles were introduced into two-component system silicone based materials. The presence of silver nanoparticles was investigated with scanning electron microscope (SEM). The antibacterial activity against Streptococcus mutans was determined. The result were statistically analysed with a Statistica 12.5 software and non-parametric Kruskal-Wallis test (α = 0.05). Findings: The silver nanoparticles introduction into RTV - silicone allowed to enhance the antimicrobial resistance against standard strain of Streptococcus mutans. Research limitations/implications: In this research only Streptococcus mutans bacterium strain was used. In future activity of presented materials against other pathogenic bacteria living in oral cavity should be determined. Additionally long term investigation should be prepared. Practical implications: The colonization of dental materials with pathogenic bacteria and fungus is one of the most important and still unresolved problems related to exposition on oral environment. The low microbiological resistance of RTV-silicones and antimicrobial potential of silver were reported in numerous studies. The gram-positive Streptococcus mutans is commonly found in the human oral cavity and it is an important factor to tooth decay. Originality/value: The resistance against Streptococcus mutans of modified material was enhanced. The investigated materials could be a potential factor a potential conducive to reducing the risk of oral cavity infections.