Abstract
A series of novel 5-substituted 2-[2-(pyridyl)ethenyl]-1,3,4-oxadiazoles were efficiently synthesized by cyclocondensation of the appropriate 3-(pyridyl)acrylohydrazides with triethyl orthoesters in the presence of glacial acetic acid. The products were identified by means of spectroscopic methods and their pK A ionization constants were determined. The influence of substituents on the basicity of the pyridine system has been discussed. Graphical Abstract: [Figure not available: see fulltext.][Figure not available: see fulltext.]
| Original language | English |
|---|---|
| Pages (from-to) | 303-311 |
| Number of pages | 9 |
| Journal | Monatshefte fur Chemie |
| Volume | 146 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2015 |
Keywords
- 1,3,4-Oxadiazoles
- 3-(Pyridyl)acrylohydrazides
- Basicity
- Cyclizations
- Heterocycles
- pK Ionization constants
ASJC Scopus subject areas
- General Chemistry
Fingerprint
Dive into the research topics of 'Study on the synthesis of novel 5-substituted 2-[2-(pyridyl)ethenyl]-1,3,4-oxadiazoles and their acid-base interactions'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver