Abstract
Sensitivity analysis has become one of the standard tools in analysis of models of intracellular processes. Various methods have been proposed, developed for either local or global sensitivity of systems under investigation. In this work, we propose a method that may be used to find potential molecular drug targets, taking into account heterogeneity of population of cells with respect to their responses to a particular drug agent.
| Translated title of the contribution | Analiza wrażliwości ukierunkowana na poszukiwanie molekularnych celów dla leków |
|---|---|
| Original language | English |
| Pages (from-to) | 197-205 |
| Number of pages | 9 |
| Journal | Mathematica Applicanda |
| Volume | 47 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2019 |
Keywords
- Molecular drug targets
- Sensitivity analysis
- Signaling pathways
ASJC Scopus subject areas
- General Mathematics
- Decision Sciences (miscellaneous)
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