On the Synthesis and Basicity of 1,3-Diaminoisoquinolines

Wojciech Zieliński; Agnieszka Kudelko

doi:10.1007/s00706-002-0543-2

On the Synthesis and Basicity of 1,3-Diaminoisoquinolines

Wojciech Zieliński
, Agnieszka Kudelko

Department of Chemical Organic Technology and Petrochemistry (RCH/RCH5)

Silesian University of Technology

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A series of 6- and 7-substituted derivatives of 1,3-diaminoisoquinoline were synthesized by the reaction of N,N-diethylarylacetamides with POCl ₃ and then with N,N-dimethylcyanamide. The products were identified by means of spectroscopic methods and their pK_a dissociation constants were determined.

Original language	English
Pages (from-to)	403-409
Number of pages	7
Journal	Monatshefte fur Chemie
Volume	134
Issue number	3
DOIs	https://doi.org/10.1007/s00706-002-0543-2
Publication status	Published - Mar 2003

Keywords

1,3-Diaminoisoquinolines
UV/Vis spectroscopy
pK values

ASJC Scopus subject areas

General Chemistry

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10.1007/s00706-002-0543-2

Cite this

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title = "On the Synthesis and Basicity of 1,3-Diaminoisoquinolines",

abstract = "A series of 6- and 7-substituted derivatives of 1,3-diaminoisoquinoline were synthesized by the reaction of N,N-diethylarylacetamides with POCl 3 and then with N,N-dimethylcyanamide. The products were identified by means of spectroscopic methods and their pKa dissociation constants were determined.",

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AU - Zieliński, Wojciech

AU - Kudelko, Agnieszka

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N2 - A series of 6- and 7-substituted derivatives of 1,3-diaminoisoquinoline were synthesized by the reaction of N,N-diethylarylacetamides with POCl 3 and then with N,N-dimethylcyanamide. The products were identified by means of spectroscopic methods and their pKa dissociation constants were determined.

AB - A series of 6- and 7-substituted derivatives of 1,3-diaminoisoquinoline were synthesized by the reaction of N,N-diethylarylacetamides with POCl 3 and then with N,N-dimethylcyanamide. The products were identified by means of spectroscopic methods and their pKa dissociation constants were determined.

KW - 1,3-Diaminoisoquinolines

KW - UV/Vis spectroscopy

KW - pK values

UR - https://www.scopus.com/pages/publications/0347510939

U2 - 10.1007/s00706-002-0543-2

DO - 10.1007/s00706-002-0543-2

M3 - Article

AN - SCOPUS:0347510939

SN - 0026-9247

VL - 134

SP - 403

EP - 409

JO - Monatshefte fur Chemie

JF - Monatshefte fur Chemie

IS - 3

ER -

On the Synthesis and Basicity of 1,3-Diaminoisoquinolines

Abstract

Keywords

ASJC Scopus subject areas

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