Multilayer evolutionary games - A new tool for modelling cancer cell heterogeneity

Andrzej Świerniak; Michał Krześlak

doi:10.2316/P.2016.832-016

Multilayer evolutionary games - A new tool for modelling cancer cell heterogeneity

Andrzej Świerniak
, Michał Krześlak

Department of Systems Biology and Engineering (RAU/RAU1)

Silesian University of Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Evolutionary game theory has been widely used to simulate tumor processes. Inter-cellular interactions that occur within tumor populations are good examples of biological evolutionary games for space and nutrients. One of the hallmarks of cancer cells is their heterogeneity which should be included in modelling their interactions. One way to do this is to introduce multilayer scheme in the spatial evolutionary games. These games are played on multiple lattices corresponding to the possible phenotypes and give possibility to simulate and investigate heterogeneity on the player-level in addition to the population-level.

Original language	English
Title of host publication	Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016
Publisher	Acta Press
Pages	38-44
Number of pages	7
ISBN (Electronic)	9780889869813
DOIs	https://doi.org/10.2316/P.2016.832-016
Publication status	Published - 2016
Event	12th IASTED International Conference on Biomedical Engineering, BioMed 2016 - Innsbruck, Austria Duration: 15 Feb 2016 → 16 Feb 2016

Publication series

Name	Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016

Conference

Conference	12th IASTED International Conference on Biomedical Engineering, BioMed 2016
Country/Territory	Austria
City	Innsbruck
Period	15/02/16 → 16/02/16

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Biomathematical modelling
Cancer
Evolutionary games
Heterogeneity
Sensitivity
Spatial effects

ASJC Scopus subject areas

Biomedical Engineering

Access to Document

10.2316/P.2016.832-016

Cite this

Świerniak, A., & Krześlak, M. (2016). Multilayer evolutionary games - A new tool for modelling cancer cell heterogeneity. In Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016 (pp. 38-44). (Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016). Acta Press. https://doi.org/10.2316/P.2016.832-016

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title = "Multilayer evolutionary games - A new tool for modelling cancer cell heterogeneity",

abstract = "Evolutionary game theory has been widely used to simulate tumor processes. Inter-cellular interactions that occur within tumor populations are good examples of biological evolutionary games for space and nutrients. One of the hallmarks of cancer cells is their heterogeneity which should be included in modelling their interactions. One way to do this is to introduce multilayer scheme in the spatial evolutionary games. These games are played on multiple lattices corresponding to the possible phenotypes and give possibility to simulate and investigate heterogeneity on the player-level in addition to the population-level.",

keywords = "Biomathematical modelling, Cancer, Evolutionary games, Heterogeneity, Sensitivity, Spatial effects",

author = "Andrzej {\'S}wierniak and Micha{\l} Krze{\'s}lak",

year = "2016",

doi = "10.2316/P.2016.832-016",

language = "English",

series = "Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016",

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booktitle = "Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016",

address = "Canada",

note = "12th IASTED International Conference on Biomedical Engineering, BioMed 2016 ; Conference date: 15-02-2016 Through 16-02-2016",

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Świerniak, A & Krześlak, M 2016, Multilayer evolutionary games - A new tool for modelling cancer cell heterogeneity. in Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016. Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016, Acta Press, pp. 38-44, 12th IASTED International Conference on Biomedical Engineering, BioMed 2016, Innsbruck, Austria, 15/02/16. https://doi.org/10.2316/P.2016.832-016

Multilayer evolutionary games - A new tool for modelling cancer cell heterogeneity. / Świerniak, Andrzej; Krześlak, Michał.
Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016. Acta Press, 2016. p. 38-44 (Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Krześlak, Michał

PY - 2016

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N2 - Evolutionary game theory has been widely used to simulate tumor processes. Inter-cellular interactions that occur within tumor populations are good examples of biological evolutionary games for space and nutrients. One of the hallmarks of cancer cells is their heterogeneity which should be included in modelling their interactions. One way to do this is to introduce multilayer scheme in the spatial evolutionary games. These games are played on multiple lattices corresponding to the possible phenotypes and give possibility to simulate and investigate heterogeneity on the player-level in addition to the population-level.

AB - Evolutionary game theory has been widely used to simulate tumor processes. Inter-cellular interactions that occur within tumor populations are good examples of biological evolutionary games for space and nutrients. One of the hallmarks of cancer cells is their heterogeneity which should be included in modelling their interactions. One way to do this is to introduce multilayer scheme in the spatial evolutionary games. These games are played on multiple lattices corresponding to the possible phenotypes and give possibility to simulate and investigate heterogeneity on the player-level in addition to the population-level.

KW - Biomathematical modelling

KW - Cancer

KW - Evolutionary games

KW - Heterogeneity

KW - Sensitivity

KW - Spatial effects

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M3 - Conference contribution

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T3 - Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016

SP - 38

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BT - Proceedings of the 12th IASTED International Conference on Biomedical Engineering, BioMed 2016

PB - Acta Press

T2 - 12th IASTED International Conference on Biomedical Engineering, BioMed 2016

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ER -

Multilayer evolutionary games - A new tool for modelling cancer cell heterogeneity

Abstract

Publication series

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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