Model of Lung Cancer Progression and Metastasis—Need for a Delay

Krzysztof Psiuk-Maksymowicz

doi:10.1007/978-3-031-38430-1_17

Model of Lung Cancer Progression and Metastasis—Need for a Delay

Krzysztof Psiuk-Maksymowicz

Department of Systems Biology and Engineering (RAU/RAU1)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

A deterministic model consisting of both an ordinary differential equation and delay differential equations was proposed to describe the problem of lung cancer growth and its metastatic progression. In order to represent the behaviour of a virtual population of affected individuals, some of the model parameters are randomly generated. This approach makes it possible to determine certain characteristics describing the population, such as the classification of the primary cancer, location of the metastasis or the estimation of survival curves.

Original language	English
Title of host publication	The Latest Developments and Challenges in Biomedical Engineering - Proceedings of the 23rd Polish Conference on Biocybernetics and Biomedical Engineering
Editors	Paweł Strumiłło, Artur Klepaczko, Michał Strzelecki, Dorota Bociąga
Publisher	Springer Science and Business Media Deutschland GmbH
Pages	215-223
Number of pages	9
ISBN (Print)	9783031384295
DOIs	https://doi.org/10.1007/978-3-031-38430-1_17
Publication status	Published - 2024
Event	Proceedings of the 23rd Polish Conference on Biocybernetics and Biomedical Engineering, PCBEE 2023 - Lodz, Poland Duration: 27 Sept 2023 → 29 Sept 2023

Publication series

Name	Lecture Notes in Networks and Systems
Volume	746 LNNS
ISSN (Print)	2367-3370
ISSN (Electronic)	2367-3389

Conference

Conference	Proceedings of the 23rd Polish Conference on Biocybernetics and Biomedical Engineering, PCBEE 2023
Country/Territory	Poland
City	Lodz
Period	27/09/23 → 29/09/23

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

DDEs
Metastasis
Modeling of lung cancer growth
ODE

ASJC Scopus subject areas

Control and Systems Engineering
Signal Processing
Computer Networks and Communications

Access to Document

10.1007/978-3-031-38430-1_17

Cite this

Psiuk-Maksymowicz, K. (2024). Model of Lung Cancer Progression and Metastasis—Need for a Delay. In P. Strumiłło, A. Klepaczko, M. Strzelecki, & D. Bociąga (Eds.), The Latest Developments and Challenges in Biomedical Engineering - Proceedings of the 23rd Polish Conference on Biocybernetics and Biomedical Engineering (pp. 215-223). (Lecture Notes in Networks and Systems; Vol. 746 LNNS). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/978-3-031-38430-1_17

Psiuk-Maksymowicz, Krzysztof. / Model of Lung Cancer Progression and Metastasis—Need for a Delay. The Latest Developments and Challenges in Biomedical Engineering - Proceedings of the 23rd Polish Conference on Biocybernetics and Biomedical Engineering. editor / Paweł Strumiłło ; Artur Klepaczko ; Michał Strzelecki ; Dorota Bociąga. Springer Science and Business Media Deutschland GmbH, 2024. pp. 215-223 (Lecture Notes in Networks and Systems).

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abstract = "A deterministic model consisting of both an ordinary differential equation and delay differential equations was proposed to describe the problem of lung cancer growth and its metastatic progression. In order to represent the behaviour of a virtual population of affected individuals, some of the model parameters are randomly generated. This approach makes it possible to determine certain characteristics describing the population, such as the classification of the primary cancer, location of the metastasis or the estimation of survival curves.",

keywords = "DDEs, Metastasis, Modeling of lung cancer growth, ODE",

author = "Krzysztof Psiuk-Maksymowicz",

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Psiuk-Maksymowicz, K 2024, Model of Lung Cancer Progression and Metastasis—Need for a Delay. in P Strumiłło, A Klepaczko, M Strzelecki & D Bociąga (eds), The Latest Developments and Challenges in Biomedical Engineering - Proceedings of the 23rd Polish Conference on Biocybernetics and Biomedical Engineering. Lecture Notes in Networks and Systems, vol. 746 LNNS, Springer Science and Business Media Deutschland GmbH, pp. 215-223, Proceedings of the 23rd Polish Conference on Biocybernetics and Biomedical Engineering, PCBEE 2023, Lodz, Poland, 27/09/23. https://doi.org/10.1007/978-3-031-38430-1_17

Model of Lung Cancer Progression and Metastasis—Need for a Delay. / Psiuk-Maksymowicz, Krzysztof.
The Latest Developments and Challenges in Biomedical Engineering - Proceedings of the 23rd Polish Conference on Biocybernetics and Biomedical Engineering. ed. / Paweł Strumiłło; Artur Klepaczko; Michał Strzelecki; Dorota Bociąga. Springer Science and Business Media Deutschland GmbH, 2024. p. 215-223 (Lecture Notes in Networks and Systems; Vol. 746 LNNS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AB - A deterministic model consisting of both an ordinary differential equation and delay differential equations was proposed to describe the problem of lung cancer growth and its metastatic progression. In order to represent the behaviour of a virtual population of affected individuals, some of the model parameters are randomly generated. This approach makes it possible to determine certain characteristics describing the population, such as the classification of the primary cancer, location of the metastasis or the estimation of survival curves.

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KW - Metastasis

KW - Modeling of lung cancer growth

KW - ODE

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Psiuk-Maksymowicz K. Model of Lung Cancer Progression and Metastasis—Need for a Delay. In Strumiłło P, Klepaczko A, Strzelecki M, Bociąga D, editors, The Latest Developments and Challenges in Biomedical Engineering - Proceedings of the 23rd Polish Conference on Biocybernetics and Biomedical Engineering. Springer Science and Business Media Deutschland GmbH. 2024. p. 215-223. (Lecture Notes in Networks and Systems). doi: 10.1007/978-3-031-38430-1_17