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Genotoxicological effects of some phenoxyherbicides and their metabolites on bacillus subtilis M45 Rec- and H17 Rec+ strains

  • Elbieta Grabińska-Sota
  • , Ewa Winiowska
  • , Joanna Kalka
  • , Beata Cieranka
  • Częstochowa University of Technology
  • Silesian University of Technology

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Because they are used in a number of commercial preparations phenoxyacetic acids and their salts can occur in wastewater. During their degradation genotoxic substances may be created. The results of investigations of biodegradability and genotoxicity of some phenoxyherbicides are presented. Commercial formulations of 2,4-D (Aminopielik 720) and MCPA (Chwastox Extra) were the substrates studied. Biodegradation tests were conducted according to OECD guidelines for testing of chemicals - confirmatory test (OECD Method 303 A). Genotoxicity tests were conducted with Bacillus subtilis strains according to the method of [Chemical Mutagens, vol. 6, Plenum Press, New York. 1980, p. 149]. Genotoxicity of biodegradation products was also studied. Both commercial formulations were biodegradable. Aminopielik 720 was potentially genotoxic but only at great concentrations while Chwastox Extra was not genotoxic. Biodegradation products of neither compound were genotoxic.

Original languageEnglish
Pages (from-to)81-85
Number of pages5
JournalChemosphere
Volume47
Issue number1
DOIs
Publication statusPublished - 2002

Keywords

  • 2,4-Dichlorophenoxyacetic acid
  • 2-Methyl-4-chlorophenoxyacetic acid
  • Bacillus subtilis
  • Biodegradation
  • Genotoxicity

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • General Chemistry
  • Pollution
  • Health, Toxicology and Mutagenesis

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