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Experimental data in modelling of intracellular processes

  • Silesian University of Technology

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

This paper deals with modeling of miRNA-mediated control of gene transcription and its relevance concerning experiments involving plasmid transfection. We show that when such experiments are used as a base for model development, the model should include usual molecular players as well as plasmid products. Otherwise, the dynamics captured by the model might be much different form the dynamics of the processes it is supposed to capture.

Original languageEnglish
Title of host publicationProceedings of the IASTED International Conference Modelling, Identification and Control, MIC 2015
PublisherActa Press
Pages105-109
Number of pages5
ISBN (Electronic)9780889869752
DOIs
Publication statusPublished - 2015
Event2015 IASTED International Conference on Modelling, Identification and Control, MIC 2015 - Innsbruck, Austria
Duration: 16 Feb 201517 Feb 2015

Publication series

NameProceedings of the IASTED International Conference on Modelling, Identification and Control
ISSN (Print)1025-8973

Conference

Conference2015 IASTED International Conference on Modelling, Identification and Control, MIC 2015
Country/TerritoryAustria
CityInnsbruck
Period16/02/1517/02/15

Keywords

  • Parameter fitting
  • Signaling pathways
  • Systems biology

ASJC Scopus subject areas

  • Software
  • Modeling and Simulation
  • Computer Science Applications

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