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Abstract

Systems for re-annotations of DNA microarray data for supporting analysis of results of DNA microarray experiments are becoming important elements of bioinformatics aspects of gene expression based studies [10]. However, due to the computational problems related to the whole genome browsing projects, available services and data for re-annotation of microarray probes are still quite sparse. The difficulty in developing systems of re-annotations of microarray probe sets is mainly in huge sizes of probe set data. In our research we have created an efficient re-annotation method by combining the well known gene search tool BLAT with appropriately designed database. The elaborated system extends possibilities of existing re-annotation tools in the sense that: (1) by tuning parameters of all steps of re-annotation procedure any Affymetrix microarray standard chip can be automatically re-annotated in few hours, (2) several Affymetrix microarray chip standards are already precomputed.

Original languageEnglish
Title of host publicationComputational Collective Intelligence
Subtitle of host publicationTechnologies and Applications - Third International Conference, ICCCI 2011, Proceedings
Pages281-289
Number of pages9
EditionPART 2
DOIs
Publication statusPublished - 2011
Event3rd International Conference on Computational Collective Intelligence, ICCCI 2011 - Gdynia, Poland
Duration: 21 Sept 201123 Sept 2011

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume6923 LNAI
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference3rd International Conference on Computational Collective Intelligence, ICCCI 2011
Country/TerritoryPoland
CityGdynia
Period21/09/1123/09/11

Keywords

  • affymetrix
  • classification
  • expression data
  • microarrays
  • re-annotation

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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