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EAST: Energy Alignment Search Tool

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

15 Citations (Scopus)

Abstract

The inspection of structural changes (in selected proteins' regions) that take place in particular reactions of signal pathways is very important for their analysis. Conformational modifications as an effect of biochemical reactions or environmental influences cause changes in the conformational energy distributions. Observations of the energy characteristics allow to detect structural changes of selected proteins. In the paper, we present the EAST - method of similarity searching based on energy profiles. This method can be employed to find similar proteins during the analysis of substrates of signal paths' reactions and to detect regions of protein structure modifications.

Original languageEnglish
Title of host publicationFuzzy Systems and Knowledge Discovery - Third International Conference, FSKD 2006, Proceedings
PublisherSpringer Verlag
Pages696-705
Number of pages10
ISBN (Print)3540459162, 9783540459163
DOIs
Publication statusPublished - 2006
Event3rd International Conference on Fuzzy Systems and Knowledge Discovery, FSKD 2006 - Xi'an, China
Duration: 24 Sept 200628 Sept 2006

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume4223 LNAI
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference3rd International Conference on Fuzzy Systems and Knowledge Discovery, FSKD 2006
Country/TerritoryChina
CityXi'an
Period24/09/0628/09/06

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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