Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate

Anna Kuźnik; Dominika Kozicka; Jakub Adamek

doi:10.3390/M1470

Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate

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1 Citation (Scopus)

Abstract

Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate was synthesized at room temperature, starting from 1-ethoxy derivative of diethyl 1-(N-acetylamino)-1-phenylmethylphosphonate via the corresponding phosphonium salt as a reactive intermediate in the Michaelis–Arbuzov-like reaction with methyl diphenylphosphinite. The structure of the compound obtained was confirmed by spectroscopic techniques (¹H, ¹³C, ³¹P NMR, IR, and MS).

Original language	English
Article number	M1470
Journal	MolBank
Volume	2022
Issue number	4
DOIs	https://doi.org/10.3390/M1470
Publication status	Published - Dec 2022

Keywords

1-phosphinoylalkylphosphonate
Michaelis–Arbuzov reaction
bisphosphonate
bisphosphoric compound

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.3390/M1470

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@article{10a4e054b347474a9f241028c3106da4,

title = "Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate",

abstract = "Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate was synthesized at room temperature, starting from 1-ethoxy derivative of diethyl 1-(N-acetylamino)-1-phenylmethylphosphonate via the corresponding phosphonium salt as a reactive intermediate in the Michaelis{\textendash}Arbuzov-like reaction with methyl diphenylphosphinite. The structure of the compound obtained was confirmed by spectroscopic techniques (1H, 13C, 31P NMR, IR, and MS).",

keywords = "1-phosphinoylalkylphosphonate, Michaelis{\textendash}Arbuzov reaction, bisphosphonate, bisphosphoric compound",

author = "Anna Ku{\'z}nik and Dominika Kozicka and Jakub Adamek",

note = "Publisher Copyright: {\textcopyright} 2022 by the authors.",

year = "2022",

month = dec,

doi = "10.3390/M1470",

language = "English",

volume = "2022",

journal = "MolBank",

issn = "1422-8599",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

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TY - JOUR

T1 - Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate

AU - Kuźnik, Anna

AU - Kozicka, Dominika

AU - Adamek, Jakub

PY - 2022/12

Y1 - 2022/12

N2 - Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate was synthesized at room temperature, starting from 1-ethoxy derivative of diethyl 1-(N-acetylamino)-1-phenylmethylphosphonate via the corresponding phosphonium salt as a reactive intermediate in the Michaelis–Arbuzov-like reaction with methyl diphenylphosphinite. The structure of the compound obtained was confirmed by spectroscopic techniques (1H, 13C, 31P NMR, IR, and MS).

AB - Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate was synthesized at room temperature, starting from 1-ethoxy derivative of diethyl 1-(N-acetylamino)-1-phenylmethylphosphonate via the corresponding phosphonium salt as a reactive intermediate in the Michaelis–Arbuzov-like reaction with methyl diphenylphosphinite. The structure of the compound obtained was confirmed by spectroscopic techniques (1H, 13C, 31P NMR, IR, and MS).

KW - 1-phosphinoylalkylphosphonate

KW - Michaelis–Arbuzov reaction

KW - bisphosphonate

KW - bisphosphoric compound

UR - https://www.scopus.com/pages/publications/85144692956

U2 - 10.3390/M1470

DO - 10.3390/M1470

M3 - Article

AN - SCOPUS:85144692956

SN - 1422-8599

VL - 2022

JO - MolBank

JF - MolBank

IS - 4

M1 - M1470

ER -

Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate

Abstract

Keywords

ASJC Scopus subject areas

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