Abstract
We compare sufficient conditions for local controllability for a class of models of treatment response to antiangiogenic and combined anticancer therapies. The combined therapy is understood as combination of direct anticancer strategy e.g. chemotherapy and indirect modality (in this case antiangiogenic therapy). We discuss different control objectives related to multimodal therapies in the light of present knowledge of self-organization of tumor cell populations treated by anticancer drugs. Controllability of the models in the form of semilinear second order dynamic systems enables to expect that the objectives could be reached.
| Original language | English |
|---|---|
| Title of host publication | 19th IFAC World Congress IFAC 2014, Proceedings |
| Editors | Xiaohua Xia, Edward Boje |
| Publisher | IFAC Secretariat |
| Pages | 11530-11535 |
| Number of pages | 6 |
| ISBN (Electronic) | 9783902823625 |
| Publication status | Published - 2014 |
| Event | 19th IFAC World Congress on International Federation of Automatic Control, IFAC 2014 - Cape Town, South Africa Duration: 24 Aug 2014 → 29 Aug 2014 |
Publication series
| Name | IFAC Proceedings Volumes (IFAC-PapersOnline) |
|---|---|
| Volume | 19 |
| ISSN (Print) | 1474-6670 |
Conference
| Conference | 19th IFAC World Congress on International Federation of Automatic Control, IFAC 2014 |
|---|---|
| Country/Territory | South Africa |
| City | Cape Town |
| Period | 24/08/14 → 29/08/14 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cancer modeling
- Constrained controllability
- Multimodal therapy
- Semilinear systems
ASJC Scopus subject areas
- Control and Systems Engineering
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