Automatic Control and Feedback Loops in Biology and Medicine

Jaroslaw Smieja

doi:10.1007/978-3-030-13273-6_1

Automatic Control and Feedback Loops in Biology and Medicine

Jaroslaw Smieja

Department of Systems Biology and Engineering (RAU/RAU1)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

Biological systems, from individual cells to cells populations, to tissue and organs to whole organisms, are equipped in multiple positive and negative feedback control mechanisms. Knowledge of these mechanisms is crucial if we want to modify intracellular biochemical control systems (in genetic engineering), affect them during therapies, control populations metabolism or behavior (e.g. in bioreactors), or design artificial organs or devices supporting physiological processes. This work focuses on three aspects of interdisciplinary research in automatic control, biology and medicine: (i) modeling of physiological processes on a whole body level, aimed at supporting artificial organs development; (ii) using optimal control theory for designing anticancer therapy protocols and (iii) using simulation and analysis techniques for identification of complex intracellular regulatory mechanisms, aimed at expanding knowledge in this field.

Original language	English
Title of host publication	Automation 2019 - Progress in Automation, Robotics and Measurement Techniques
Editors	Roman Szewczyk, Cezary Zielinski, Malgorzata Kaliczynska
Publisher	Springer Verlag
Pages	3-12
Number of pages	10
ISBN (Print)	9783030132729
DOIs	https://doi.org/10.1007/978-3-030-13273-6_1
Publication status	Published - 2020
Event	International Conference on Progress in Automation, Robotics and Measurement Techniques, AUTOMATION 2019 - Warsaw, Poland Duration: 27 Mar 2019 → 29 Mar 2019

Publication series

Name	Advances in Intelligent Systems and Computing
Volume	920
ISSN (Print)	2194-5357

Conference

Conference	International Conference on Progress in Automation, Robotics and Measurement Techniques, AUTOMATION 2019
Country/Territory	Poland
City	Warsaw
Period	27/03/19 → 29/03/19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Biomedical systems
Modeling
Optimization
Systems biology

ASJC Scopus subject areas

Control and Systems Engineering
General Computer Science

Access to Document

10.1007/978-3-030-13273-6_1

Cite this

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title = "Automatic Control and Feedback Loops in Biology and Medicine",

abstract = "Biological systems, from individual cells to cells populations, to tissue and organs to whole organisms, are equipped in multiple positive and negative feedback control mechanisms. Knowledge of these mechanisms is crucial if we want to modify intracellular biochemical control systems (in genetic engineering), affect them during therapies, control populations metabolism or behavior (e.g. in bioreactors), or design artificial organs or devices supporting physiological processes. This work focuses on three aspects of interdisciplinary research in automatic control, biology and medicine: (i) modeling of physiological processes on a whole body level, aimed at supporting artificial organs development; (ii) using optimal control theory for designing anticancer therapy protocols and (iii) using simulation and analysis techniques for identification of complex intracellular regulatory mechanisms, aimed at expanding knowledge in this field.",

keywords = "Biomedical systems, Modeling, Optimization, Systems biology",

author = "Jaroslaw Smieja",

note = "Publisher Copyright: {\textcopyright} Springer Nature Switzerland AG 2020.; International Conference on Progress in Automation, Robotics and Measurement Techniques, AUTOMATION 2019 ; Conference date: 27-03-2019 Through 29-03-2019",

year = "2020",

doi = "10.1007/978-3-030-13273-6\_1",

language = "English",

isbn = "9783030132729",

series = "Advances in Intelligent Systems and Computing",

publisher = "Springer Verlag",

pages = "3--12",

editor = "Roman Szewczyk and Cezary Zielinski and Malgorzata Kaliczynska",

booktitle = "Automation 2019 - Progress in Automation, Robotics and Measurement Techniques",

address = "Germany",

}

Smieja, J 2020, Automatic Control and Feedback Loops in Biology and Medicine. in R Szewczyk, C Zielinski & M Kaliczynska (eds), Automation 2019 - Progress in Automation, Robotics and Measurement Techniques. Advances in Intelligent Systems and Computing, vol. 920, Springer Verlag, pp. 3-12, International Conference on Progress in Automation, Robotics and Measurement Techniques, AUTOMATION 2019, Warsaw, Poland, 27/03/19. https://doi.org/10.1007/978-3-030-13273-6_1

Automatic Control and Feedback Loops in Biology and Medicine. / Smieja, Jaroslaw.
Automation 2019 - Progress in Automation, Robotics and Measurement Techniques. ed. / Roman Szewczyk; Cezary Zielinski; Malgorzata Kaliczynska. Springer Verlag, 2020. p. 3-12 (Advances in Intelligent Systems and Computing; Vol. 920).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Automatic Control and Feedback Loops in Biology and Medicine

AU - Smieja, Jaroslaw

N1 - Publisher Copyright: © Springer Nature Switzerland AG 2020.

PY - 2020

Y1 - 2020

N2 - Biological systems, from individual cells to cells populations, to tissue and organs to whole organisms, are equipped in multiple positive and negative feedback control mechanisms. Knowledge of these mechanisms is crucial if we want to modify intracellular biochemical control systems (in genetic engineering), affect them during therapies, control populations metabolism or behavior (e.g. in bioreactors), or design artificial organs or devices supporting physiological processes. This work focuses on three aspects of interdisciplinary research in automatic control, biology and medicine: (i) modeling of physiological processes on a whole body level, aimed at supporting artificial organs development; (ii) using optimal control theory for designing anticancer therapy protocols and (iii) using simulation and analysis techniques for identification of complex intracellular regulatory mechanisms, aimed at expanding knowledge in this field.

AB - Biological systems, from individual cells to cells populations, to tissue and organs to whole organisms, are equipped in multiple positive and negative feedback control mechanisms. Knowledge of these mechanisms is crucial if we want to modify intracellular biochemical control systems (in genetic engineering), affect them during therapies, control populations metabolism or behavior (e.g. in bioreactors), or design artificial organs or devices supporting physiological processes. This work focuses on three aspects of interdisciplinary research in automatic control, biology and medicine: (i) modeling of physiological processes on a whole body level, aimed at supporting artificial organs development; (ii) using optimal control theory for designing anticancer therapy protocols and (iii) using simulation and analysis techniques for identification of complex intracellular regulatory mechanisms, aimed at expanding knowledge in this field.

KW - Biomedical systems

KW - Modeling

KW - Optimization

KW - Systems biology

UR - https://www.scopus.com/pages/publications/85062290720

U2 - 10.1007/978-3-030-13273-6_1

DO - 10.1007/978-3-030-13273-6_1

M3 - Conference contribution

AN - SCOPUS:85062290720

SN - 9783030132729

T3 - Advances in Intelligent Systems and Computing

SP - 3

EP - 12

BT - Automation 2019 - Progress in Automation, Robotics and Measurement Techniques

A2 - Szewczyk, Roman

A2 - Zielinski, Cezary

A2 - Kaliczynska, Malgorzata

PB - Springer Verlag

T2 - International Conference on Progress in Automation, Robotics and Measurement Techniques, AUTOMATION 2019

Y2 - 27 March 2019 through 29 March 2019

ER -

Automatic Control and Feedback Loops in Biology and Medicine

Abstract

Publication series

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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