Abstract
We report on the synthesis of 2-deoxyglycosyl derivatives of uridine as potential donor substrates for glycosyltransferases. The totally stereoselective synthesis is accomplished by two sequential addition reactions of uridine derivatives to glycals promoted by triphenylphosphine-hydrogen bromide.
| Original language | English |
|---|---|
| Pages (from-to) | 401-416 |
| Number of pages | 16 |
| Journal | Bioorganic Chemistry |
| Volume | 35 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Oct 2007 |
Keywords
- GTs substrate analogues
- Glycals
- Stereoselective synthesis
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Drug Discovery
- Organic Chemistry
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